SCREENING ANTIBACTERIAL ACTIVITY OF Ni(II) CYSTINE COMPLEX AGAINST PATHOGENIC BACTERIA

The effect of nickel complex containing with cystine against some pathogenic bacteria such as Bacillus subtilis, Salmonella typhi, Shigelladysenteriae, Shigellaflexneriae, Staphylococcus aureus and Streptococcus-b-haemolyticus. The antibacterial activity of Ni(II) cystinecomplex was established too. Disc diffusion methods were used and two types disc were used like Sample discs Ni(II) complex and Standard discs (Kanamycin). Among the discs Ni(II) cystine complex had antibacterial activity. At the dose of 100 mg/disc the Ni(II) cystine complex showed little diameter to zone of inhibition within the range of 5-15mm. On the other hand, kanamycin showed the diameter of zone of inhibition within the range of 17-25 mm at the dose of 30mg/disc. The dose of 200 mg/disc of Ni(II) cystine complex showed the diameter of zone of inhibition within the range of 9-20 mm which was quite comparable with kanamycin and were showed moderate sensitivity than kanamycin.